| Index | Tuscumbia | Alabama | National |
| Cost of living | 83 | 89 | 100 |
| Goods & Services | 90 | 95 | 100 |
| Groceries | 93 | 98 | 100 |
| Health care | 82 | 91 | 100 |
| Housing | 67 | 74 | 100 |
| Transportation | 88 | 90 | 100 |
| Utilities | 91 | 98 | 100 |


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| Cost of living index | |
| Goods & Services index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $87,386 | $7,282 | $2,039 | $2,622 |
| Renters | $43,019 | $3,585 | $1,004 | $1,291 |
| State | General Sales Tax | With Max Surtax |
| Alabama | 4% | 13.5% |
| State | Income Tax (Low) | Income Tax (High) |
| Alabama | 2% | 5% |
| Item | Tuscumbia | National avg. | Difference |
| Haircut | $18.95 | $27.62 | 31.4% |
| Beauty Salon | $38.84 | $51.11 | 24.0% |
| Toothpaste | $4.06 | $4.09 | 0.8% |
| Shampoo | $1.58 | $1.54 | 2.5% |
| Movie | $11.90 | $12.88 | 7.6% |
| Yoga | $15.03 | $19.66 | 23.6% |
| Item | Tuscumbia | National avg. | Difference |
| Ground Beef | $7.53 | $7.70 | 2.3% |
| Fried Chicken | $1.45 | $1.66 | 12.8% |
| Milk | $4.48 | $4.73 | 5.3% |
| Potatoes | $5.28 | $5.26 | 0.4% |
| Pizza | $12.13 | $12.76 | 5.0% |
| Beer | $10.11 | $10.55 | 4.2% |
| Item | Tuscumbia | National avg. | Difference |
| Optometrist | $79.86 | $140.06 | 43.0% |
| Doctor | $88.35 | $153.82 | 42.6% |
| Dentist | $95.66 | $123.15 | 22.3% |
| Ibuprofen | $11.39 | $11.73 | 2.9% |
| Lipitor | $26.44 | $23.61 | 12.0% |
| Item | Tuscumbia | National avg. | Difference |
| Home Price | $210,273.00 | $326,622.00 | 35.6% |
| Avg. Mortgage Payment | $1,916.69 | $2,480.25 | 22.7% |
| Apartment Rent | $1,049.00 | $1,444.00 | 27.4% |
| Item | Tuscumbia | National avg. | Difference |
| Gasoline | $2.74 | $3.06 | 10.4% |
| Tire Balancing | $54.25 | $65.21 | 16.8% |
| Item | Tuscumbia | National avg. | Difference |
| All Electricity | $190.82 | $220.12 | 13.3% |
| Phone | $193.75 | $195.71 | 1.0% |
| City | Population | Cost of Living Index | National Avg. |
| Leighton, AL | 806 | 76 | 24.4% |
| Cherokee, AL | 898 | 79 | 21.3% |
| Russellville, AL | 10,174 | 80 | 19.8% |
| Sheffield, AL | 9,116 | 81 | 18.7% |
| Underwood-Petersville, AL | 2,778 | 82 | 18.2% |
| Tuscumbia, AL | 8,741 | 83 | 17.0% |
| City | Population | Cost of Living Index | National Avg. |
| Perryville, MO | 8,741 | 89 | 11.0% |
| Dalhart, TX | 8,740 | 85 | 14.7% |
| Fallon, NV | 8,742 | 98 | 2.2% |
| Park Hills, MO | 8,743 | 81 | 18.9% |
| Malverne, NY | 8,738 | 157 | 56.8% |
| Tuscumbia, AL | 8,741 | 83 | 17.0% |