| Index | Perryville | Missouri | National |
| Cost of living | 91 | 90 | 100 |
| Groceries | 97 | 96 | 100 |
| Health care | 96 | 97 | 100 |
| Housing | 78 | 77 | 100 |
| Transportation | 99 | 96 | 100 |
| Utilities | 98 | 95 | 100 |
| Lifestyle & Entertainment | 95 | 95 | 100 |
| Household Items | 99 | 97 | 100 |
| Education & Childcare | 96 | 95 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $113,120 | $9,427 | $2,639 | $3,394 |
| Renters | $38,534 | $3,211 | $899 | $1,156 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| City | Population | Cost of Living Index | National Avg. |
| Biehle, MO | 29 | 97 | 3.0% |
| Brewer, MO | 484 | 97 | 3.0% |
| Lithium, MO | 92 | 97 | 3.0% |
| Rockwood, IL | 26 | 78 | 21.9% |
| St. Mary, MO | 266 | 84 | 16.4% |
| Perryville, MO | 8,741 | 91 | 8.6% |
| City | Population | Cost of Living Index | National Avg. |
| Tuscumbia, AL | 8,741 | 87 | 13.2% |
| Dalhart, TX | 8,740 | 91 | 9.1% |
| Fallon, NV | 8,742 | 102 | 2.2% |
| Park Hills, MO | 8,743 | 83 | 17.0% |
| Malverne, NY | 8,738 | 152 | 51.5% |
| Perryville, MO | 8,741 | 91 | 8.6% |