| Index | Puxico | Missouri | National |
| Income per capita | $20,732 | $27,044 | $29,829 |
| Median household income | $48,690 | $49,593 | $55,322 |
| Median income owner occupied | $51,750 | $62,242 | $70,586 |
| Median income renter occupied | $34,097 | $30,016 | $35,192 |
| Median earnings male | $39,009 | $34,901 | $36,919 |
| Median earnings female | $30,900 | $24,771 | $26,250 |
| Unemployment rate | 3.8% | 4.1% | 4.7% |
| Poverty level | 10.2% | 15.3% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 1.5% | 1.5% |
| Manufacturing sector | 28.2% | 28.2% |
| Financial & insurance services | 1.2% | 1.2% |
| Wholesale & retail services | 3.1% | 3.1% |
| Public administration | 8.9% | 8.9% |
| Transportation, warehousing & utilities | 6.6% | 6.6% |
| Education, health & social services | 10.8% | 10.8% |
| Other | 39.8% | 39.8% |
| City | Population | Household Income | National Avg. |
| Fisk, MO | 562 | $45,577 | 17.6% |
| Advance, MO | 1,430 | $40,125 | 27.5% |
| Bloomfield, MO | 2,404 | $39,458 | 28.7% |
| Dexter, MO | 7,867 | $39,339 | 28.9% |
| Poplar Bluff, MO | 16,979 | $35,603 | 35.6% |
| Puxico, MO | 1,133 | $48,690 | 12.0% |
| City | Population | Household Income | National Avg. |
| Cottonwood, AL | 1,133 | $27,125 | 51.0% |
| Steele, AL | 1,133 | $60,408 | 9.2% |
| Wickes, AR | 1,133 | $24,750 | 55.3% |
| Fairmead, CA | 1,133 | $45,801 | 17.2% |
| Lake Telemark, NJ | 1,133 | $149,148 | 169.6% |
| Puxico, MO | 1,133 | $48,690 | 12.0% |