| Index | Poplar Bluff | Missouri | National |
| Income per capita | $30,393 | $39,715 | $44,883 |
| Median household income | $53,468 | $72,613 | $81,333 |
| Median income owner occupied | $72,166 | $90,986 | $106,172 |
| Median income renter occupied | $29,801 | $45,210 | $52,080 |
| Median earnings male | $35,129 | $52,324 | $54,343 |
| Median earnings female | $27,780 | $36,971 | $38,439 |
| Unemployment rate | 4.3% | 4.4% | 4.9% |
| Poverty level | 26.6% | 15.3% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 12.7% | 12.7% |
| Manufacturing sector | 23.7% | 23.7% |
| Financial & insurance services | 0.7% | 0.7% |
| Wholesale & retail services | 18.8% | 18.8% |
| Public administration | 2.1% | 2.1% |
| Transportation, warehousing & utilities | 6.4% | 6.4% |
| Education, health & social services | 10.6% | 10.6% |
| Other | 24.9% | 24.9% |
| City | Population | Household Income | National Avg. |
| Puxico, MO | 1,177 | $72,398 | 11.0% |
| Fisk, MO | 578 | $68,220 | 16.1% |
| Fairdealing, MO | 470 | $59,975 | 26.3% |
| Williamsville, MO | 346 | $59,018 | 27.4% |
| Oxly, MO | 102 | $46,129 | 43.3% |
| Poplar Bluff, MO | 17,570 | $53,468 | 34.3% |
| City | Population | Household Income | National Avg. |
| Wayne, MI | 17,566 | $71,400 | 12.2% |
| Springfield, TN | 17,576 | $71,850 | 11.7% |
| East Cleveland, OH | 17,563 | $33,398 | 58.9% |
| Islip, NY | 17,559 | $164,412 | 102.1% |
| South Ogden, UT | 17,591 | $104,892 | 29.0% |
| Poplar Bluff, MO | 17,570 | $53,468 | 34.3% |