| Index | Puxico | Missouri | National |
| Cost of living | 82 | 90 | 100 |
| Groceries | 97 | 96 | 100 |
| Health care | 96 | 97 | 100 |
| Housing | 46 | 77 | 100 |
| Transportation | 99 | 96 | 100 |
| Utilities | 98 | 95 | 100 |
| Lifestyle & Entertainment | 95 | 95 | 100 |
| Household Items | 99 | 97 | 100 |
| Education & Childcare | 96 | 95 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $76,374 | $6,365 | $1,782 | $2,291 |
| Renters | $50,228 | $4,186 | $1,172 | $1,507 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| City | Population | Cost of Living Index | National Avg. |
| Zalma, MO | 62 | 76 | 24.5% |
| Bloomfield, MO | 2,482 | 82 | 18.2% |
| Dexter, MO | 8,103 | 84 | 16.4% |
| Advance, MO | 1,468 | 85 | 14.9% |
| Poplar Bluff, MO | 17,570 | 86 | 14.1% |
| Puxico, MO | 1,177 | 82 | 18.2% |
| City | Population | Cost of Living Index | National Avg. |
| Rossville, IL | 1,177 | 86 | 14.2% |
| Richfield Springs, NY | 1,177 | 95 | 4.5% |
| Holgate, OH | 1,177 | 84 | 16.4% |
| Republic, WA | 1,177 | 103 | 2.9% |
| John d'Or Prairie 215, AB | 1,177 | n/a | |
| Puxico, MO | 1,177 | 82 | 18.2% |