| Index | Puxico | Missouri | National |
| Median home price | $124,213 | $249,551 | $326,622 |
| Median rent asked | $952 | $1,140 | $1,444 |
| Avg. people per household | 2.7 | 2.4 | 2.6 |
| Owner occupied households | 69.8% | 66.8% | 63.6% |
| Renter occupied households | 30.3% | 33.2% | 36.4% |

| Population | Home Price | National Avg. | |
| Zalma, MO | 62 | $83,106 | 75% |
| Bloomfield, MO | 2,482 | $122,267 | 63% |
| Dexter, MO | 8,103 | $150,342 | 54% |
| Advance, MO | 1,468 | $182,634 | 44% |
| Poplar Bluff, MO | 17,570 | $185,443 | 43% |
| Puxico, MO | 1,177 | $124,213 | 62% |
| Population | Home Price | National Avg. | |
| Richfield Springs, NY | 1,177 | $191,396 | 41% |
| Holgate, OH | 1,177 | $162,079 | 50% |
| Rossville, IL | 1,177 | $148,034 | 55% |
| Republic, WA | 1,177 | $284,474 | 13% |
| Wellsville, MO | 1,176 | $118,712 | 64% |
| Puxico, MO | 1,177 | $124,213 | 62% |