| Index | Perryville | Missouri | National |
| Average Test Scores | 41% | 44% | 48% |
| Student/Teacher ratio | 15:1 | 14:1 | 16:1 |
| Total public schools | 5 | 1,899 | 79,221 |
| Total private schools | 3 | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | Perryville | Missouri | National |
| Completed 8th grade | 83.8% | 86.0% | 84.3% |
| Completed high school | 79.8% | 84.2% | 83.0% |
| Completed some college | 43.8% | 57.7% | 59.4% |
| Completed associate degree | 23.5% | 35.2% | 38.5% |
| Completed bachelors | 17.7% | 27.6% | 30.3% |
| Completed masters | 6.5% | 10.4% | 11.5% |
| Completed professional degree | 2.2% | 2.8% | 3.3% |
| Completed doctorate | 0.5% | 1.2% | 1.3% |
There are a total of 5 public schools, 3 private schools and n/a post-secondary schools in Perryville. Using the proficiency score averages, the average test scores for Perryville, MO schools is 41%. The average student to teacher ratio is 15:1. In Perryville, MO, an average of 83.8% of students have completed 8th grade and an average of 79.8% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Chester, IL | 8,448 | 27% | 43.2% |
| Perryville, MO | 8,741 | 41% | 14.2% |
| City | Population | Avg. Test Scores | National Avg. |
| Tuscumbia, AL | 8,741 | 42% | 12.7% |
| Fallon, NV | 8,742 | 43% | 10.2% |
| Dalhart, TX | 8,740 | 37% | 22.2% |
| Park Hills, MO | 8,743 | 48% | 0.3% |
| Malverne, NY | 8,738 | 71% | 48.4% |
| Perryville, MO | 8,741 | 41% | 14.2% |
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