| Index | Karnes City | Texas | National |
| Cost of living | 85 | 94 | 100 |
| Groceries | 101 | 98 | 100 |
| Health care | 98 | 98 | 100 |
| Housing | 52 | 83 | 100 |
| Transportation | 96 | 98 | 100 |
| Utilities | 106 | 103 | 100 |
| Lifestyle & Entertainment | 94 | 98 | 100 |
| Household Items | 98 | 98 | 100 |
| Education & Childcare | 100 | 98 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $82,023 | $6,835 | $1,914 | $2,461 |
| Renters | $61,729 | $5,144 | $1,440 | $1,852 |
| State | General Sales Tax | With Max Surtax |
| Texas | 6.25% | 8.25% |
| State | Income Tax (Low) | Income Tax (High) |
| Texas | 0% | 0% |
| City | Population | Cost of Living Index | National Avg. |
| Runge, TX | 1,217 | 81 | 19.2% |
| Kenedy, TX | 3,467 | 87 | 13.4% |
| Falls City, TX | 1,025 | 93 | 6.8% |
| Poth, TX | 1,872 | 100 | 0.4% |
| Karnes City, TX | 3,519 | 85 | 15.1% |
| City | Population | Cost of Living Index | National Avg. |
| Tipton, CA | 3,519 | 110 | 9.7% |
| Dunham, QC | 3,519 | n/a | |
| Eielson AFB, AK | 3,518 | 142 | 41.5% |
| Elizabethtown, NC | 3,517 | 92 | 8.3% |
| Red Oak, NC | 3,517 | 102 | 2.2% |
| Karnes City, TX | 3,519 | 85 | 15.1% |