| Index | Karnes City | Texas | National |
| Income per capita | $24,961 | $41,777 | $44,883 |
| Median household income | $76,554 | $80,880 | $81,333 |
| Median income owner occupied | $82,023 | $107,635 | $106,172 |
| Median income renter occupied | $61,729 | $54,463 | $52,080 |
| Median earnings male | $47,329 | $53,620 | $54,343 |
| Median earnings female | $0 | $36,296 | $38,439 |
| Unemployment rate | 1.2% | 4.3% | 4.9% |
| Poverty level | 22.4% | 16.7% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 13.0% | 13.0% |
| Manufacturing sector | 10.0% | 10.0% |
| Financial & insurance services | 0.3% | 0.3% |
| Wholesale & retail services | 3.4% | 3.4% |
| Public administration | 17.0% | 17.0% |
| Transportation, warehousing & utilities | 11.1% | 11.1% |
| Education, health & social services | 7.0% | 7.0% |
| Other | 30.8% | 30.8% |
| City | Population | Household Income | National Avg. |
| Falls City, TX | 1,025 | $106,836 | 31.4% |
| Poth, TX | 1,872 | $102,328 | 25.8% |
| Kenedy, TX | 3,467 | $55,253 | 32.1% |
| Runge, TX | 1,217 | $49,395 | 39.3% |
| Karnes City, TX | 3,519 | $76,554 | 5.9% |
| City | Population | Household Income | National Avg. |
| Tipton, CA | 3,519 | $67,378 | 17.2% |
| Dunham, QC | 3,519 | n/a | |
| Eielson AFB, AK | 3,518 | $105,587 | 29.8% |
| Elizabethtown, NC | 3,517 | $32,682 | 59.8% |
| Red Oak, NC | 3,517 | $107,689 | 32.4% |
| Karnes City, TX | 3,519 | $76,554 | 5.9% |