| Index | Karnes City | Texas | National |
| Median home price | $138,191 | $256,744 | $326,622 |
| Median rent asked | $1,079 | $1,363 | $1,444 |
| Avg. people per household | 2.8 | 2.8 | 2.6 |
| Owner occupied households | 76.9% | 61.9% | 63.6% |
| Renter occupied households | 23.1% | 38.1% | 36.4% |

| Population | Home Price | National Avg. | |
| Runge, TX | 1,217 | $134,429 | 59% |
| Kenedy, TX | 3,467 | $142,258 | 56% |
| Falls City, TX | 1,025 | $184,294 | 44% |
| Poth, TX | 1,872 | $276,204 | 15% |
| Karnes City, TX | 3,519 | $138,191 | 58% |
| Population | Home Price | National Avg. | |
| Tipton, CA | 3,519 | $283,202 | 13% |
| Eielson AFB, AK | 3,518 | $0 | 100% |
| Red Oak, NC | 3,517 | $367,056 | 12% |
| Haworth, NJ | 3,521 | $1,246,319 | 282% |
| Elizabethtown, NC | 3,517 | $218,372 | 33% |
| Karnes City, TX | 3,519 | $138,191 | 58% |