| Index | Wise | Virginia | National |
| Average Test Scores | 89% | 79% | 48% |
| Student/Teacher ratio | 14:1 | 13:1 | 16:1 |
| Total public schools | 6 | 1,596 | 79,221 |
| Total private schools | 1 | 553 | 24,874 |
| Total post-secondary schools | 1 | 199 | 7,963 |

| Index | Wise | Virginia | National |
| Completed 8th grade | 83.2% | 85.9% | 84.3% |
| Completed high school | 78.8% | 84.7% | 83.0% |
| Completed some college | 56.4% | 64.1% | 59.4% |
| Completed associate degree | 26.0% | 44.2% | 38.5% |
| Completed bachelors | 21.3% | 36.9% | 30.3% |
| Completed masters | 6.7% | 15.7% | 11.5% |
| Completed professional degree | 4.1% | 4.2% | 3.3% |
| Completed doctorate | 2.3% | 1.7% | 1.3% |
There are a total of 6 public schools, 1 private schools and 1 post-secondary schools in Wise. Using the proficiency score averages, the average test scores for Wise, VA schools is 89%. The average student to teacher ratio is 14:1. In Wise, VA, an average of 83.2% of students have completed 8th grade and an average of 78.8% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Pound, VA | 1,005 | 94% | 94.8% |
| St. Paul, VA | 888 | 91% | 89.6% |
| Coeburn, VA | 1,513 | 90% | 87.8% |
| Big Stone Gap, VA | 5,403 | 89% | 84.7% |
| Norton, VA | 4,088 | 87% | 81.6% |
| Wise, VA | 3,031 | 89% | 84.9% |
| City | Population | Avg. Test Scores | National Avg. |
| Cutchogue, NY | 3,031 | 59% | 21.9% |
| Warsaw, NY | 3,032 | 49% | 2.6% |
| Girard, PA | 3,030 | 71% | 47.9% |
| Hildale, UT | 3,030 | 32% | 33.3% |
| Denver, NC | 3,029 | 63% | 32.1% |
| Wise, VA | 3,031 | 89% | 84.9% |