Wise, VA has a population of 3,145 and is the 8,570th largest city in the United States. The population density is 1,035 per sq mi which is 441% higher than the Virginia average and 1043% higher than the national average. The median age in Wise is 40 which is approximately 4% higher than the Virginia average of 38. In Wise, 56% of the population over 15 years of age are married, 98% speak English and 1% speak Spanish. 68% of Wise residents were born in Virginia, 30% were born out of state, 0% were born outside of the United States and 1% were foreign born.