| Index | Prairie Home | Missouri | National |
| Cost of living | 83 | 90 | 100 |
| Groceries | 99 | 96 | 100 |
| Health care | 95 | 97 | 100 |
| Housing | 50 | 77 | 100 |
| Transportation | 98 | 96 | 100 |
| Utilities | 97 | 95 | 100 |
| Lifestyle & Entertainment | 96 | 95 | 100 |
| Household Items | 96 | 97 | 100 |
| Education & Childcare | 98 | 95 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $59,994 | $5,000 | $1,400 | $1,800 |
| Renters | $51,330 | $4,278 | $1,198 | $1,540 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| City | Population | Cost of Living Index | National Avg. |
| McBaine, MO | 8 | 97 | 2.7% |
| Huntsdale, MO | 21 | 97 | 2.7% |
| Franklin, MO | 127 | 97 | 2.7% |
| Lupus, MO | 23 | 80 | 20.3% |
| Clarksburg, MO | 289 | 81 | 18.8% |
| Prairie Home, MO | 252 | 83 | 16.9% |
| City | Population | Cost of Living Index | National Avg. |
| Moose Pass, AK | 252 | 128 | 28.3% |
| Malcolm, AL | 252 | 75 | 25.0% |
| McNeal, AZ | 252 | 86 | 13.8% |
| Hornbrook, CA | 252 | 107 | 7.1% |
| Jakin, GA | 252 | 86 | 14.2% |
| Prairie Home, MO | 252 | 83 | 16.9% |