| Index | Prairie Home | Missouri | National |
| Income per capita | $33,692 | $39,715 | $44,883 |
| Median household income | $56,193 | $72,613 | $81,333 |
| Median income owner occupied | $59,994 | $90,986 | $106,172 |
| Median income renter occupied | $51,330 | $45,210 | $52,080 |
| Median earnings male | $46,544 | $52,324 | $54,343 |
| Median earnings female | $32,668 | $36,971 | $38,439 |
| Unemployment rate | 1.5% | 4.4% | 4.9% |
| Poverty level | 6.2% | 15.3% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 13.5% | 13.5% |
| Manufacturing sector | 9.6% | 9.6% |
| Financial & insurance services | 0.0% | 0.0% |
| Wholesale & retail services | 21.2% | 21.2% |
| Public administration | 9.6% | 9.6% |
| Transportation, warehousing & utilities | 7.7% | 7.7% |
| Education, health & social services | 9.6% | 9.6% |
| Other | 19.2% | 19.2% |
| City | Population | Household Income | National Avg. |
| Windsor Place, MO | 400 | $127,848 | 57.2% |
| St. Martins, MO | 1,205 | $96,171 | 18.2% |
| Pierpont, MO | 74 | $95,429 | 17.3% |
| Columbia, MO | 125,431 | $79,655 | 2.1% |
| California, MO | 4,585 | $74,414 | 8.5% |
| Prairie Home, MO | 252 | $56,193 | 30.9% |
| City | Population | Household Income | National Avg. |
| Moose Pass, AK | 252 | $115,487 | 42.0% |
| Malcolm, AL | 252 | $32,143 | 60.5% |
| McNeal, AZ | 252 | $100,430 | 23.5% |
| Hornbrook, CA | 252 | $41,355 | 49.2% |
| Jakin, GA | 252 | $65,789 | 19.1% |
| Prairie Home, MO | 252 | $56,193 | 30.9% |