| Index | Poplar Bluff | Missouri | National |
| Income per capita | $20,461 | $27,044 | $29,829 |
| Median household income | $35,603 | $49,593 | $55,322 |
| Median income owner occupied | $48,623 | $62,242 | $70,586 |
| Median income renter occupied | $20,107 | $30,016 | $35,192 |
| Median earnings male | $23,477 | $34,901 | $36,919 |
| Median earnings female | $19,077 | $24,771 | $26,250 |
| Unemployment rate | 4.1% | 4.1% | 4.7% |
| Poverty level | 26.6% | 15.3% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 12.7% | 12.7% |
| Manufacturing sector | 23.7% | 23.7% |
| Financial & insurance services | 0.7% | 0.7% |
| Wholesale & retail services | 18.8% | 18.8% |
| Public administration | 2.1% | 2.1% |
| Transportation, warehousing & utilities | 6.4% | 6.4% |
| Education, health & social services | 10.6% | 10.6% |
| Other | 24.9% | 24.9% |
| City | Population | Household Income | National Avg. |
| Puxico, MO | 1,133 | $48,690 | 12.0% |
| Fisk, MO | 562 | $45,577 | 17.6% |
| Fairdealing, MO | 459 | $40,391 | 27.0% |
| Williamsville, MO | 336 | $40,250 | 27.2% |
| Oxly, MO | 99 | $30,577 | 44.7% |
| Poplar Bluff, MO | 16,979 | $35,603 | 35.6% |
| City | Population | Household Income | National Avg. |
| La Marque, TX | 16,983 | $50,464 | 8.8% |
| Ojus, FL | 16,972 | $48,248 | 12.8% |
| Lake Mary, FL | 16,987 | $92,441 | 67.1% |
| Edmundston, NB | 16,970 | n/a | |
| Islip, NY | 16,965 | $109,857 | 98.6% |
| Poplar Bluff, MO | 16,979 | $35,603 | 35.6% |