| Index | New Melle | Missouri | National |
| Cost of living | 120 | 90 | 100 |
| Groceries | 95 | 96 | 100 |
| Health care | 98 | 97 | 100 |
| Housing | 177 | 77 | 100 |
| Transportation | 97 | 96 | 100 |
| Utilities | 97 | 95 | 100 |
| Lifestyle & Entertainment | 98 | 95 | 100 |
| Household Items | 96 | 97 | 100 |
| Education & Childcare | 91 | 95 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $144,102 | $12,009 | $3,362 | $4,323 |
| Renters | $0 | $0 | $0 | $0 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| City | Population | Cost of Living Index | National Avg. |
| Defiance, MO | 70 | 96 | 4.3% |
| Three Creeks, MO | 4 | 96 | 4.3% |
| Marthasville, MO | 2,476 | 91 | 9.3% |
| Truesdale, MO | 824 | 91 | 9.2% |
| Warrenton, MO | 8,685 | 91 | 9.0% |
| New Melle, MO | 443 | 120 | 20.3% |
| City | Population | Cost of Living Index | National Avg. |
| Ravenden, AR | 443 | 80 | 20.0% |
| Robbins, CA | 443 | 131 | 31.3% |
| East Cape Girardeau, IL | 443 | 83 | 17.1% |
| Crofton, KY | 443 | 78 | 21.8% |
| Kaleva, MI | 443 | 83 | 16.6% |
| New Melle, MO | 443 | 120 | 20.3% |