| Index | Nettleton | Mississippi | National |
| Average Test Scores | 39% | 40% | 48% |
| Student/Teacher ratio | 15:1 | 16:1 | 16:1 |
| Total public schools | 4 | 893 | 79,221 |
| Total private schools | n/a | 206 | 24,874 |
| Total post-secondary schools | n/a | 68 | 7,963 |
| Index | Nettleton | Mississippi | National |
| Completed 8th grade | 69.0% | 78.6% | 84.3% |
| Completed high school | 64.8% | 76.7% | 83.0% |
| Completed some college | 35.1% | 52.5% | 59.4% |
| Completed associate degree | 22.6% | 29.8% | 38.5% |
| Completed bachelors | 10.3% | 21.0% | 30.3% |
| Completed masters | 4.5% | 7.9% | 11.5% |
| Completed professional degree | 0.4% | 2.2% | 3.3% |
| Completed doctorate | 0.4% | 0.9% | 1.3% |
There are a total of 4 public schools, n/a private schools and n/a post-secondary schools in Nettleton. Using the proficiency score averages, the average test scores for Nettleton, MS schools is 39%. The average student to teacher ratio is 15:1. In Nettleton, MS, an average of 69.0% of students have completed 8th grade and an average of 64.8% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Smithville, MS | 628 | 63% | 31.3% |
| Mooreville, MS | 2,138 | 56% | 15.6% |
| Tupelo, MS | 38,251 | 55% | 13.5% |
| Amory, MS | 6,873 | 54% | 11.5% |
| Fulton, MS | 3,968 | 48% | 1.0% |
| Nettleton, MS | 2,455 | 39% | 19.0% |
| City | Population | Avg. Test Scores | National Avg. |
| Ware Shoals, SC | 2,455 | 49% | 1.4% |
| Canton, MO | 2,455 | 40% | 17.7% |
| Driggs, ID | 2,454 | 36% | 25.3% |
| New Palestine, IN | 2,456 | 61% | 26.9% |
| McConnelsville, OH | 2,456 | 72% | 50.0% |
| Nettleton, MS | 2,455 | 39% | 19.0% |
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