| Index | Doniphan | Missouri | National |
| Average Test Scores | 35% | 44% | 48% |
| Student/Teacher ratio | 12:1 | 14:1 | 16:1 |
| Total public schools | 7 | 1,899 | 79,221 |
| Total private schools | 2 | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | Doniphan | Missouri | National |
| Completed 8th grade | 74.5% | 86.0% | 84.3% |
| Completed high school | 70.4% | 84.2% | 83.0% |
| Completed some college | 41.2% | 57.7% | 59.4% |
| Completed associate degree | 16.7% | 35.2% | 38.5% |
| Completed bachelors | 12.0% | 27.6% | 30.3% |
| Completed masters | 3.0% | 10.4% | 11.5% |
| Completed professional degree | 0.7% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of 7 public schools, 2 private schools and n/a post-secondary schools in Doniphan. Using the proficiency score averages, the average test scores for Doniphan, MO schools is 35%. The average student to teacher ratio is 12:1. In Doniphan, MO, an average of 74.5% of students have completed 8th grade and an average of 70.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Naylor, MO | 753 | 51% | 5.7% |
| Corning, AR | 3,168 | 44% | 8.3% |
| Maynard, AR | 455 | 33% | 30.7% |
| Doniphan, MO | 2,528 | 35% | 27.3% |
| City | Population | Avg. Test Scores | National Avg. |
| Ware Shoals, SC | 2,527 | 49% | 1.4% |
| Carleton, MI | 2,527 | 43% | 10.6% |
| Hamilton City, CA | 2,529 | 33% | 31.3% |
| Lincoln, AR | 2,530 | 41% | 14.6% |
| Nettleton, MS | 2,530 | 39% | 19.0% |
| Doniphan, MO | 2,528 | 35% | 27.3% |
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