| Index | Kirksville | Missouri | National |
| Median home price | $209,836 | $249,551 | $326,622 |
| Median rent asked | $984 | $1,140 | $1,444 |
| Avg. people per household | 2.4 | 2.4 | 2.6 |
| Owner occupied households | 48.5% | 66.8% | 63.6% |
| Renter occupied households | 51.5% | 33.2% | 36.4% |

| Population | Home Price | National Avg. | |
| Worthington, MO | 115 | $0 | 100% |
| South Gifford, MO | 62 | $0 | 100% |
| Hurdland, MO | 144 | $44,072 | 87% |
| Gibbs, MO | 68 | $56,330 | 83% |
| Novinger, MO | 347 | $80,614 | 75% |
| Kirksville, MO | 18,120 | $209,836 | 36% |
| Population | Home Price | National Avg. | |
| New Philadelphia, OH | 18,121 | $223,975 | 31% |
| Zachary, LA | 18,126 | $413,758 | 27% |
| Bon Air, VA | 18,126 | $460,140 | 41% |
| Bay City, TX | 18,090 | $189,871 | 42% |
| Tiffin, OH | 18,151 | $181,209 | 45% |
| Kirksville, MO | 18,120 | $209,836 | 36% |