| Statistic | Reportedincidents | /100k people | Kirksville/100k people | Missouri/100k people | National/100k people |
| Total crime | 411 | n/a (estimate) | 2,352 | 2,403 | 2,119 |
| Murder | 1 | n/a | 5.7 | 7.8 | 5.0 |
| Rape | 10 | n/a | 57.2 | 45.2 | 37.5 |
| Robbery | 3 | n/a | 17.2 | 51.5 | 60.6 |
| Assault | 59 | n/a | 337.7 | 357.5 | 256.1 |
| Violent crime | 73 | n/a (estimate) | 418 | 462 | 359 |
| Burglary | 45 | n/a | 257.6 | 236.3 | 229.2 |
| Theft | 274 | n/a | 1,568.2 | 1,306.5 | 1,272.1 |
| Vehicle theft | 19 | n/a | 108.7 | 398.4 | 258.8 |
| Property crime | 338 | n/a (estimate) | 1,935 | 1,941 | 1,760 |

Crime can be categorized into two primary types: violent and property crimes. Violent crimes encompass offenses such as murder, rape, robbery, and assault, whereas property crimes involve acts like burglary, theft, and vehicle theft. The overall crime rate in Kirksville is 11% higher than the national average. Specifically, there were 73 violent crimes reported in Kirksville, equivalent to 418 per 100,000 residents, which is higher than the national average by 16.4%. Additionally, Kirksville recorded 338 property crimes, amounting to 1935 per 100,000 people, higher than the national average by 9.9%.
When evaluating the Kirksville crime rate for every 100,000 residents, it positions itself in the middle range among all cities that reported crime. Our examination of total offenses, spanning both violent and property crimes, indicates that the reported Kirksville crime rates closely correspond to the national average reported by other regions.
Kirksville maintains a property crime rate that closely resembles the national norm. In Kirksville, 1935 property crimes were reported, aligning with the national average of 1760 per 100,000 individuals. Consequently, the area's safety profile stands on par with the average city, neither significantly safer nor more dangerous. This consistency underscores a balanced commitment to community safety and security, providing residents with a stable and reassuring living environment.
AreaVibes conducted surveys inquiring about the safety perception of Kirksville residents. Out of the respondents (25 in total), 32% expressed a strong sense of security, believing that crime rates in Kirksville were low, and they felt comfortable walking alone at night. Conversely, 68% held a contrasting viewpoint, expressing concerns about safety in the area and feeling uncomfortable walking alone during the nighttime hours.
Determining whether Kirksville is a place to live may not always yield a simple answer, given the city's varying safety levels across different areas. Nonetheless, comprehending the city's overall crime rate can be a valuable asset. In broad terms, Kirksville has an overall crime rate that is 11% higher than the national average. When we take a look at crime on a daily basis, this translates into 1.13 daily occurrences, comprising 0.2 violent crimes and 0.93 property crimes. Scrutinizing these statistics provides a foundation for a more informed assessment of the suitability of Kirksville as a potential place to establish residency.
Examining year-over-year crime data provides insights into short-term trends with regards to the crime activity in Kirksville. This analysis involves comparing crime rates from one year to the next, enabling the identification of patterns and fluctuations in crime. Such information proves invaluable to residents seeking to make well-informed decisions about their choice of residence. In the most recent year, compared to the previous one, total crime in Kirksville has decreased by 48.8%. Specifically, violent crime has decreased by 13.1%, while property crime has decreased by 53%. This data empowers individuals with a clearer understanding of the evolving safety landscape in Kirksville.
Kirksville has a poverty rate that stands at 28.8, in contrast to the national average of 15.1. Historically, a direct correlation has been observed between poverty rates and crime stats. Higher poverty rates have led to higher crime rates, while lower poverty rates have led to a reduction in Kirksville crime rates. Income disparities and heightened poverty levels can serve as catalysts for elevated or reduced criminal activity, as individuals may or may not turn to illicit means to fulfill their basic needs. This could be one of many factors that may influence crime.
If employment opportunities are limited or if many jobs offer low wages, it can lead to higher rates of unemployment and underemployment, which could lead to an increase in Kirksville crime rates. Areas where individuals struggle with unemployment or low wages, may be more susceptible to an increase in criminal activities as a result of financial insecurity. While lower rates of unemployment or a surplus of job opportunities could lead to a decrease in crime as their basic needs are being met. Kirksville has an unemployment rate of 4.5%, compared to a national average of 4.9%.
Highly populated regions typically encompass expansive urban hubs teeming with diverse economic prospects. Within these areas, income inequality can be exacerbated, giving rise to enclaves of poverty amid affluence. Communities marked by economic disparities may contend with heightened property crimes, and in certain instances, violent crimes. Conversely, regions characterized by low population density often exhibit lower Kirksville crime rates. For instance, in Kirksville, the population density stands at 1259.6 people per square mile, diverging from the national average of 90.6 people per square mile.

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| Item | Kirksville | Missouri | National |
| Law enforcement employees (officers & civilians) | 25 | 12,115 | 558,732 |
| Police officers & civilians /1000 residents | 1.4 | 3.7 | 3.3 |
| State | Total offenders | Missouri /100K | National /100K |
| Missouri | 19,657 | 344 | 266 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| La Plata, MO | 1,231 | 81 | 162 | 243 |
| Greentop, MO | 612 | 597 | 2,506 | 3,103 |
| Brashear, MO | 149 | 630 | 2,647 | 3,277 |
| Millard, MO | 75 | 641 | 2,693 | 3,334 |
| Queen City, MO | 726 | 664 | 2,788 | 3,452 |
| Novinger, MO | 347 | 734 | 3,085 | 3,819 |
| Hurdland, MO | 144 | 746 | 3,135 | 3,881 |
| Kirksville, MO | 18,120 | 418 | 1,935 | 2,352 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| New Philadelphia, OH | 18,121 | 115 | 513 | 628 |
| Bon Air, VA | 18,126 | 203 | 1,461 | 1,664 |
| Zachary, LA | 18,126 | 333 | 2,021 | 2,353 |
| Bay City, TX | 18,090 | 580 | 2,844 | 3,424 |
| Tiffin, OH | 18,151 | 356 | 1,876 | 2,232 |
| Kirksville, MO | 18,120 | 418 | 1,935 | 2,352 |