| Index | Hannibal | Missouri | National |
| Income per capita | $36,247 | $39,715 | $44,883 |
| Median household income | $68,324 | $72,613 | $81,333 |
| Median income owner occupied | $93,632 | $90,986 | $106,172 |
| Median income renter occupied | $45,055 | $45,210 | $52,080 |
| Median earnings male | $48,944 | $52,324 | $54,343 |
| Median earnings female | $32,033 | $36,971 | $38,439 |
| Unemployment rate | 3.3% | 4.4% | 4.9% |
| Poverty level | 19.1% | 15.3% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 10.9% | 10.9% |
| Manufacturing sector | 30.2% | 30.2% |
| Financial & insurance services | 1.4% | 1.4% |
| Wholesale & retail services | 17.0% | 17.0% |
| Public administration | 4.8% | 4.8% |
| Transportation, warehousing & utilities | 5.6% | 5.6% |
| Education, health & social services | 11.3% | 11.3% |
| Other | 18.4% | 18.4% |
| City | Population | Household Income | National Avg. |
| Rensselaer, MO | 265 | $116,738 | 43.5% |
| Kinderhook, IL | 316 | $97,505 | 19.9% |
| Payson, IL | 1,427 | $93,443 | 14.9% |
| Palmyra, MO | 3,744 | $76,047 | 6.5% |
| New London, MO | 936 | $75,130 | 7.6% |
| Hannibal, MO | 17,980 | $68,324 | 16.0% |
| City | Population | Household Income | National Avg. |
| Tillmans Corner, AL | 17,980 | $65,286 | 19.7% |
| Palmview, TX | 17,983 | $57,175 | 29.7% |
| Loyalist, ON | 17,983 | n/a | |
| Manassas Park, VA | 17,985 | $122,960 | 51.2% |
| Iselin, NJ | 17,973 | $148,071 | 82.1% |
| Hannibal, MO | 17,980 | $68,324 | 16.0% |