| Index | Clayton | Illinois | National |
| Average Test Scores | n/a | 33% | 48% |
| Student/Teacher ratio | n/a | 18:1 | 16:1 |
| Total public schools | n/a | 3,938 | 79,221 |
| Total private schools | n/a | 1,438 | 24,874 |
| Total post-secondary schools | n/a | 306 | 7,963 |


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| Index | Clayton | Illinois | National |
| Completed 8th grade | 72.6% | 86.2% | 84.3% |
| Completed high school | 69.9% | 84.7% | 83.0% |
| Completed some college | 33.6% | 61.8% | 59.4% |
| Completed associate degree | 15.1% | 40.7% | 38.5% |
| Completed bachelors | 3.9% | 32.9% | 30.3% |
| Completed masters | 1.4% | 12.7% | 11.5% |
| Completed professional degree | 0.0% | 3.4% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Clayton. Using the proficiency score averages, the average test scores for Clayton, IL schools is n/a. The average student to teacher ratio is n/a. In Clayton, IL, an average of 72.6% of students have completed 8th grade and an average of 69.9% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Liberty, IL | 398 | 41% | 15.1% |
| Bowen, IL | 583 | 40% | 17.7% |
| Camp Point, IL | 1,144 | 31% | 36.5% |
| Augusta, IL | 605 | 30% | 38.5% |
| Mount Sterling, IL | 2,220 | 29% | 39.9% |
| Clayton, IL | 585 | n/a |
| City | Population | Avg. Test Scores | National Avg. |
| Jamesport, MO | 585 | 53% | 9.4% |
| Naselle, WA | 585 | 60% | 24.0% |
| Silverhill, AL | 585 | 56% | 15.6% |
| Mead, NE | 585 | 60% | 24.5% |
| Patoka, IL | 585 | 29% | 39.6% |
| Clayton, IL | 585 | n/a |