| Index | Tuscumbia | Missouri | National |
| Income per capita | $21,427 | $39,715 | $44,883 |
| Median household income | $102,200 | $72,613 | $81,333 |
| Median income owner occupied | $111,341 | $90,986 | $106,172 |
| Median income renter occupied | $0 | $45,210 | $52,080 |
| Median earnings male | $0 | $52,324 | $54,343 |
| Median earnings female | $39,363 | $36,971 | $38,439 |
| Unemployment rate | 3.3% | 4.4% | 4.9% |
| Poverty level | 2.0% | 15.3% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 55.0% | 55.0% |
| Manufacturing sector | 10.0% | 10.0% |
| Financial & insurance services | 0.0% | 0.0% |
| Wholesale & retail services | 10.0% | 10.0% |
| Public administration | 20.0% | 20.0% |
| Transportation, warehousing & utilities | 0.0% | 0.0% |
| Education, health & social services | 5.0% | 5.0% |
| Other | 0.0% | 0.0% |
| City | Population | Household Income | National Avg. |
| Olean, MO | 69 | $136,773 | 68.2% |
| St. Elizabeth, MO | 459 | $116,110 | 42.8% |
| Lake Ozark, MO | 2,401 | $114,799 | 41.1% |
| St. Thomas, MO | 303 | $106,606 | 31.1% |
| Village of Four Seasons, MO | 2,160 | $100,500 | 23.6% |
| Tuscumbia, MO | 167 | $102,200 | 25.7% |
| City | Population | Household Income | National Avg. |
| Tomales, CA | 167 | $165,298 | 103.2% |
| Rock Falls, IA | 167 | $66,824 | 17.8% |
| Westphalia, IA | 167 | $120,484 | 48.1% |
| Ferris, IL | 167 | $64,381 | 20.8% |
| Colburn, IN | 167 | $44,725 | 45.0% |
| Tuscumbia, MO | 167 | $102,200 | 25.7% |