Santa Ana, CA has a population of 333,605 and is the 57th largest city in the United States. The population density is 12,290 per sq mi which is 5188% higher than the California average and 13465% higher than the national average. The median age in Santa Ana is 31 which is approximately 15% lower than the California average of 36. In Santa Ana, 49% of the population over 15 years of age are married, 18% speak English and 71% speak Spanish. 48% of Santa Ana residents were born in California, 5% were born out of state, 1% were born outside of the United States and 46% were foreign born.