| Index | Sanibel | Florida | National | 
| Cost of living | 162 | 98 | 100 | 
| Goods & Services | 105 | 98 | 100 | 
| Groceries | 99 | 99 | 100 | 
| Health care | 108 | 96 | 100 | 
| Housing | 302 | 96 | 100 | 
| Transportation | 107 | 99 | 100 | 
| Utilities | 96 | 97 | 100 | 

 
				
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				| Cost of living index | |
| Goods & Services index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | 
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) | 
| Owners | $108,906 | $9,076 | $2,541 | $3,268 | 
| Renters | $36,879 | $3,073 | $860 | $1,106 | 
| State | General Sales Tax | With Max Surtax | 
| Florida | 6% | 7.5% | 
| State | Income Tax (Low) | Income Tax (High) | 
| Florida | 0% | 0% | 
| Item | Sanibel | National avg. | Difference | 
| Haircut | $28.20 | $24.26 | 16.2% | 
| Beauty Salon | $54.05 | $45.56 | 18.6% | 
| Toothpaste | $3.63 | $3.70 | 1.9% | 
| Shampoo | $1.45 | $1.28 | 13.5% | 
| Movie | $13.05 | $12.13 | 7.6% | 
| Bowling | $21.20 | $18.00 | 17.8% | 
| Item | Sanibel | National avg. | Difference | 
| Ground Beef | $6.06 | $5.84 | 3.8% | 
| Fried Chicken | $1.40 | $1.57 | 11.0% | 
| Milk | $4.57 | $4.67 | 2.2% | 
| Potatoes | $5.24 | $4.93 | 6.1% | 
| Pizza | $11.72 | $12.09 | 3.0% | 
| Beer | $11.06 | $10.41 | 6.2% | 
| Item | Sanibel | National avg. | Difference | 
| Optometrist | $101.67 | $125.68 | 19.1% | 
| Doctor | $153.94 | $135.78 | 13.4% | 
| Dentist | $122.09 | $113.29 | 7.8% | 
| Ibuprofen | $10.59 | $10.65 | 0.6% | 
| Lipitor | $535.04 | $468.60 | 14.2% | 
| Item | Sanibel | National avg. | Difference | 
| Home Price | $703,800.00 | $184,700.00 | 281.1% | 
| Avg. Mortgage Payment | $2,422.46 | $2,346.69 | 3.2% | 
| Apartment Rent | $1,100.00 | $949.00 | 15.9% | 
| Item | Sanibel | National avg. | Difference | 
| Gasoline | $3.47 | $3.46 | 0.2% | 
| Tire Balancing | $74.92 | $59.92 | 25.0% | 
| Item | Sanibel | National avg. | Difference | 
| All Electricity | $179.36 | $193.99 | 7.5% | 
| Phone | $194.07 | $192.25 | 0.9% | 
| City | Population | Cost of Living Index | National Avg. | 
| Pine Manor, FL | 4,582 | 95 | 5.1% | 
| Harlem Heights, FL | 1,362 | 95 | 4.7% | 
| Page Park, FL | 621 | 99 | 0.9% | 
| Cypress Lake, FL | 12,766 | 103 | 3.4% | 
| Villas, FL | 14,421 | 104 | 4.1% | 
| Sanibel, FL | 7,378 | 162 | 62.4% | 
| City | Population | Cost of Living Index | National Avg. | 
| Ben Lomond, CA | 7,378 | 190 | 90.0% | 
| Edwardsburgh/Cardinal, ON | 7,376 | n/a | |
| St. Gabriel, LA | 7,374 | 95 | 4.6% | 
| Highland Heights, KY | 7,372 | 94 | 6.3% | 
| Saint-Philippe, QC | 7,384 | n/a | |
| Sanibel, FL | 7,378 | 162 | 62.4% |