| Statistic | Reportedincidents | /100k people | Perryville/100k people | Missouri/100k people | National/100k people |
| Total crime | 101 | n/a (estimate) | 1,190 | 2,403 | 2,119 |
| Murder | 0 | n/a | 0.0 | 7.8 | 5.0 |
| Rape | 4 | n/a | 47.1 | 45.2 | 37.5 |
| Robbery | 0 | n/a | 0.0 | 51.5 | 60.6 |
| Assault | 21 | n/a | 247.4 | 357.5 | 256.1 |
| Violent crime | 25 | n/a (estimate) | 294 | 462 | 359 |
| Burglary | 6 | n/a | 70.7 | 236.3 | 229.2 |
| Theft | 61 | n/a | 718.6 | 1,306.5 | 1,272.1 |
| Vehicle theft | 9 | n/a | 106.0 | 398.4 | 258.8 |
| Property crime | 76 | n/a (estimate) | 895 | 1,941 | 1,760 |

Crime is typically categorized into two main types: violent and property crimes. Violent crimes encompass offenses such as murder, rape, robbery, and assault, while property crimes include burglary, theft, and vehicle theft. Based on the most recent report, the Perryville crime rate is lower than the national average by 43.9%. Specifically, there were 25 violent crimes in Perryville, equivalent to 294 per 100,000 individuals, lower than the national average by 18%. Furthermore, Perryville recorded 76 property crimes, amounting to 895 per 100,000 residents, which was lower than the average by 49.1%.
Perryville showcased a dedication to violent crime safety in its latest reported crime year by achieving a murder rate of 0. This accomplishment could indicate that it is a safe place for residents, but also provides a shining example to other urban areas endeavoring to create safer communities.
To get a feel for the safety of living in Perryville, it's essential to analyze both the overall crime rate and the daily incident count. Perryville presents a total crime rate that is 44% lower than the national average per 100,000 residents. Consequently, Perryville experiences an average of 0.28 daily crimes, comprising 0.07 violent incidents and 0.21 property-related offenses. This evaluation offers a comprehensive understanding of the safety landscape, aiding individuals in making informed decisions when considering relocation.
Year-over-year crime data allows residents and potential residents to assess the crime in Perryville. A decrease in crime rates may indicate improving safety, while an increase could raise concerns. The year-over-year crime rate in Perryville has decreased by 38.4%. Violent crimes have decreased by 34.2%, while property crimes have decreased by 39.7%. By comparing crime rates from one year to the next, authorities and communities can identify trends and patterns in criminal activity. This helps in understanding whether crime is increasing, decreasing, or remaining stable over time.
Perryville has a population density of 1107.7 people per square mile, contrasting with the national average of 90.6 people per square mile. High population density cities are often large urban hubs teeming with diverse economic opportunities. Within these environments, income disparities can become pronounced, leading to higher poverty levels. This economic divide may contribute to an uptick in property crimes and, occasionally, violent crimes. In contrast, areas characterized by low population density typically exhibit lower Perryville crime rates.
In Perryville, the median home price stands at $256,524, diverging from the national average of $326,622. Elevated housing costs often induce financial strain among residents. When individuals grapple with the challenges of affording housing, they may find themselves compelled to resort to criminal activities as a means of addressing their financial hardships, including acts like theft or fraud. This predicament is particularly pronounced in areas where housing affordability poses a persistent issue, giving rise to heightened concerns regarding crime. In such instances, some individuals and families may find themselves constrained to reside in cramped or subpar housing conditions, exacerbating stress levels and potentially fostering domestic disputes and associated criminal incidents.
In Perryville, the average rental rates are $1,116 per month, compared to the national average of $1,444. Rapid increases in rental costs can lead to neighborhood instability as residents are forced to move frequently in search of more affordable housing. This transience can weaken community bonds and hinder the establishment of social support networks, which can indirectly contribute to crime. While affordable rent and areas with higher income per capita, allow for long term renters and community bonds to the formed, therefore reducing crime rates on the long term.

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| Item | Perryville | Missouri | National |
| Law enforcement employees (officers & civilians) | 28 | 12,115 | 558,732 |
| Police officers & civilians /1000 residents | 3.4 | 3.7 | 3.3 |
| State | Total offenders | Missouri /100K | National /100K |
| Missouri | 19,657 | 344 | 266 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| Chester, IL | 8,448 | 45 | 268 | 313 |
| Ozora, MO | 113 | 418 | 1,755 | 2,172 |
| Longtown, MO | 130 | 422 | 1,773 | 2,195 |
| Sedgewickville, MO | 159 | 472 | 1,981 | 2,452 |
| Frohna, MO | 328 | 486 | 2,042 | 2,528 |
| Rockwood, IL | 26 | 418 | 2,481 | 2,899 |
| Old Appleton, MO | 73 | 636 | 2,672 | 3,308 |
| Perryville, MO | 8,741 | 294 | 895 | 1,190 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| Tuscumbia, AL | 8,741 | 65 | 445 | 510 |
| Fallon, NV | 8,742 | 207 | 1,149 | 1,356 |
| Dalhart, TX | 8,740 | 168 | 829 | 997 |
| Park Hills, MO | 8,743 | 148 | 2,065 | 2,213 |
| Malverne, NY | 8,738 | 133 | 604 | 737 |
| Perryville, MO | 8,741 | 294 | 895 | 1,190 |