McLain, MS has a population of 440 and is the 20,345th largest city in the United States. The population density is 130 per sq mi which is 111% higher than the Mississippi average and 43% higher than the national average. The median age in McLain is 42 which is approximately 16% higher than the Mississippi average of 37. In McLain, 45% of the population over 15 years of age are married, 100% speak English and 0% speak Spanish. 74% of McLain residents were born in Mississippi, 26% were born out of state, 0% were born outside of the United States and 0% were foreign born.