Manzanola, CO has a population of 452 and is the 20,176th largest city in the United States. The population density is 1,636 per sq mi which is 3185% higher than the Colorado average and 1705% higher than the national average. The median age in Manzanola is 46 which is approximately 26% higher than the Colorado average of 36. In Manzanola, 42% of the population over 15 years of age are married, 75% speak English and 25% speak Spanish. 66% of Manzanola residents were born in Colorado, 25% were born out of state, 0% were born outside of the United States and 8% were foreign born.