Lewis Run, PA has a population of 627 and is the 18,155th largest city in the United States. The population density is 360 per sq mi which is 30% higher than the Pennsylvania average and 297% higher than the national average. The median age in Lewis Run is 45 which is approximately 11% higher than the Pennsylvania average of 41. In Lewis Run, 66% of the population over 15 years of age are married, 98% speak English and 1% speak Spanish. 83% of Lewis Run residents were born in Pennsylvania, 16% were born out of state, 0% were born outside of the United States and 0% were foreign born.