Jefferson City, MO has a population of 43,143 and is the 952nd largest city in the United States. The population density is 1,196 per sq mi which is 1284% higher than the Missouri average and 1220% higher than the national average. The median age in Jefferson City is 37 which is approximately 2% lower than the Missouri average of 38. In Jefferson City, 49% of the population over 15 years of age are married, 95% speak English and 2% speak Spanish. 70% of Jefferson City residents were born in Missouri, 25% were born out of state, 1% were born outside of the United States and 4% were foreign born.