| Index | Isola | Mississippi | National |
| Average Test Scores | n/a | 40% | 48% |
| Student/Teacher ratio | n/a | 16:1 | 16:1 |
| Total public schools | n/a | 893 | 79,221 |
| Total private schools | n/a | 206 | 24,874 |
| Total post-secondary schools | n/a | 68 | 7,963 |

| Index | Isola | Mississippi | National |
| Completed 8th grade | 66.0% | 78.6% | 84.3% |
| Completed high school | 61.4% | 76.7% | 83.0% |
| Completed some college | 35.7% | 52.5% | 59.4% |
| Completed associate degree | 15.5% | 29.8% | 38.5% |
| Completed bachelors | 12.9% | 21.0% | 30.3% |
| Completed masters | 7.2% | 7.9% | 11.5% |
| Completed professional degree | 0.9% | 2.2% | 3.3% |
| Completed doctorate | 0.0% | 0.9% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Isola. Using the proficiency score averages, the average test scores for Isola, MS schools is n/a. The average student to teacher ratio is n/a. In Isola, MS, an average of 66.0% of students have completed 8th grade and an average of 61.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Inverness, MS | 863 | 42% | 12.5% |
| Moorhead, MS | 1,549 | 30% | 38.5% |
| Indianola, MS | 9,550 | 29% | 39.3% |
| Hollandale, MS | 2,053 | 23% | 51.6% |
| Belzoni, MS | 2,196 | 14% | 70.1% |
| Isola, MS | 787 | n/a |
| City | Population | Avg. Test Scores | National Avg. |
| Unalakleet, AK | 787 | 37% | 22.9% |
| Bettsville, OH | 787 | 67% | 39.6% |
| Hornbeck, LA | 787 | 85% | 76.0% |
| Mound City, KS | 787 | 31% | 35.9% |
| Minto, ND | 786 | 45% | 6.8% |
| Isola, MS | 787 | n/a |