Holyoke, MA has a population of 40,280 and is the 1,027th largest city in the United States. The population density is 1,894 per sq mi which is 201% higher than the Massachusetts average and 1991% higher than the national average. The median age in Holyoke is 34 which is approximately 13% lower than the Massachusetts average of 39. In Holyoke, 41% of the population over 15 years of age are married, 54% speak English and 42% speak Spanish. 56% of Holyoke residents were born in Massachusetts, 16% were born out of state, 21% were born outside of the United States and 7% were foreign born.