| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 36°F | 56°F | 45°F | 5.0" |
| February | 37°F | 58°F | 47°F | 4.7" |
| March | 46°F | 70°F | 57°F | 3.6" |
| April | 53°F | 77°F | 64°F | 5.4" |
| May | 62°F | 84°F | 72°F | 6.0" |
| June | 69°F | 91°F | 80°F | 2.4" |
| July | 71°F | 92°F | 81°F | 4.3" |
| August | 72°F | 94°F | 81°F | 3.3" |
| September | 66°F | 87°F | 75°F | 8.7" |
| October | 52°F | 77°F | 63°F | 5.9" |
| November | 44°F | 69°F | 55°F | 3.1" |
| December | 37°F | 59°F | 47°F | 5.5" |
| Index | Holcomb | Mississippi | National |
| Air quality index | 33 | 40 | 42 |
| Pollution index | 1,793,620 | 1,514,109 | 2,726,193 |
| Measurement | Total |
| Days measured | 101 |
| Days with good air quality | 77 |
| Days with moderate air quality | 24 |
| Days w/ poor A.Q. for sensitive groups | |
| Days with unhealthy air quality |
| Pollutant | Total |
| Arsenic | 0.040% |
| Benzene | 0.020% |
| Carbon Tetrachloride | 0.010% |
| Lead | 0.010% |
| Mercury | 0.001% |
| City | Population | Air Quality Index | National Avg. |
| Duck Hill, MS | 981 | 33 | 34.0% |
| Elliott, MS | 768 | 33 | 34.0% |
| Grenada, MS | 12,349 | 33 | 34.0% |
| Holcomb, MS | 330 | 33 | 34.0% |
| City | Population | Air Quality Index | National Avg. |
| Coffeeville, AL | 330 | 36 | 28.0% |
| Strong, AR | 330 | 35 | 30.0% |
| Littlefield, AZ | 330 | 44 | 12.0% |
| So-Hi, AZ | 330 | 13 | 74.0% |
| Kawela Bay, HI | 330 | 30 | 40.0% |
| Holcomb, MS | 330 | 33 | 34.0% |
Here are the best places to live in Mississippi
See the best places to live in & around Holcomb
10 Best cities in Mississippi for employment
These are the 10 most affordable cities in Mississippi