| Index | Fredericktown | Missouri | National |
| Income per capita | $33,625 | $39,715 | $44,883 |
| Median household income | $56,173 | $72,613 | $81,333 |
| Median income owner occupied | $70,662 | $90,986 | $106,172 |
| Median income renter occupied | $33,674 | $45,210 | $52,080 |
| Median earnings male | $41,858 | $52,324 | $54,343 |
| Median earnings female | $36,859 | $36,971 | $38,439 |
| Unemployment rate | 2.9% | 4.4% | 4.9% |
| Poverty level | 18.1% | 15.3% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 15.9% | 15.9% |
| Manufacturing sector | 29.5% | 29.5% |
| Financial & insurance services | 0.0% | 0.0% |
| Wholesale & retail services | 21.7% | 21.7% |
| Public administration | 3.5% | 3.5% |
| Transportation, warehousing & utilities | 7.9% | 7.9% |
| Education, health & social services | 9.7% | 9.7% |
| Other | 11.8% | 11.8% |
| City | Population | Household Income | National Avg. |
| Cherokee Pass, MO | 271 | $77,802 | 4.3% |
| Marquand, MO | 198 | $47,743 | 41.3% |
| Mine La Motte, MO | 399 | $47,693 | 41.4% |
| Junction City, MO | 277 | $46,112 | 43.3% |
| Cobalt, MO | 217 | $44,591 | 45.2% |
| Fredericktown, MO | 4,146 | $56,173 | 30.9% |
| City | Population | Household Income | National Avg. |
| Lakewood, IL | 4,146 | $223,843 | 175.2% |
| Rosewood Heights, IL | 4,146 | $121,285 | 49.1% |
| Paintsville, KY | 4,145 | $32,251 | 60.3% |
| McLoud, OK | 4,147 | $78,775 | 3.1% |
| San Joaquin, CA | 4,144 | $56,242 | 30.8% |
| Fredericktown, MO | 4,146 | $56,173 | 30.9% |