| Index | De Soto | Wisconsin | National |
| Cost of living | 85 | 96 | 100 |
| Groceries | 100 | 99 | 100 |
| Health care | 99 | 98 | 100 |
| Housing | 52 | 89 | 100 |
| Transportation | 95 | 98 | 100 |
| Utilities | 104 | 101 | 100 |
| Lifestyle & Entertainment | 101 | 98 | 100 |
| Household Items | 100 | 99 | 100 |
| Education & Childcare | 96 | 98 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $132,744 | $11,062 | $3,097 | $3,983 |
| Renters | $40,601 | $3,383 | $947 | $1,218 |
| State | General Sales Tax | With Max Surtax |
| Wisconsin | 5% | 6.75% |
| State | Income Tax (Low) | Income Tax (High) |
| Wisconsin | 3.54% | 7.65% |
| City | Population | Cost of Living Index | National Avg. |
| New Albin, IA | 522 | 86 | 13.8% |
| Eitzen, MN | 285 | 87 | 12.8% |
| Mount Sterling, WI | 134 | 88 | 12.1% |
| Lynxville, WI | 115 | 88 | 11.8% |
| Caledonia, MN | 2,816 | 88 | 11.7% |
| De Soto, WI | 525 | 85 | 14.8% |
| City | Population | Cost of Living Index | National Avg. |
| La Paz Valley, AZ | 525 | 103 | 2.6% |
| Buckley, IL | 525 | 86 | 14.3% |
| Reynolds, IN | 525 | 85 | 15.4% |
| Grosse Tete, LA | 525 | 88 | 12.0% |
| South Range, MI | 525 | 83 | 17.3% |
| De Soto, WI | 525 | 85 | 14.8% |