| Index | Clarksville | Missouri | National |
| Income per capita | $44,677 | $39,715 | $44,883 |
| Median household income | $78,402 | $72,613 | $81,333 |
| Median income owner occupied | $116,670 | $90,986 | $106,172 |
| Median income renter occupied | $59,833 | $45,210 | $52,080 |
| Median earnings male | $72,636 | $52,324 | $54,343 |
| Median earnings female | $40,241 | $36,971 | $38,439 |
| Unemployment rate | 2.5% | 4.4% | 4.9% |
| Poverty level | 11.2% | 15.3% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 25.5% | 25.5% |
| Manufacturing sector | 32.7% | 32.7% |
| Financial & insurance services | 0.0% | 0.0% |
| Wholesale & retail services | 8.2% | 8.2% |
| Public administration | 0.0% | 0.0% |
| Transportation, warehousing & utilities | 9.2% | 9.2% |
| Education, health & social services | 6.1% | 6.1% |
| Other | 16.3% | 16.3% |
| City | Population | Household Income | National Avg. |
| Annada, MO | 61 | $70,209 | 13.7% |
| Eolia, MO | 313 | $67,911 | 16.5% |
| Louisiana, MO | 3,368 | $67,278 | 17.3% |
| Pleasant Hill, IL | 1,145 | $65,982 | 18.9% |
| Time, IL | 17 | $58,309 | 28.3% |
| Clarksville, MO | 525 | $78,402 | 3.6% |
| City | Population | Household Income | National Avg. |
| La Paz Valley, AZ | 525 | $45,245 | 44.4% |
| Buckley, IL | 525 | $85,456 | 5.1% |
| Reynolds, IN | 525 | $82,158 | 1.0% |
| Grosse Tete, LA | 525 | $68,646 | 15.6% |
| South Range, MI | 525 | $45,194 | 44.4% |
| Clarksville, MO | 525 | $78,402 | 3.6% |