| Index | Clarksville | Missouri | National |
| Cost of living | 79 | 90 | 100 |
| Groceries | 95 | 96 | 100 |
| Health care | 98 | 97 | 100 |
| Housing | 39 | 77 | 100 |
| Transportation | 97 | 96 | 100 |
| Utilities | 97 | 95 | 100 |
| Lifestyle & Entertainment | 98 | 95 | 100 |
| Household Items | 96 | 97 | 100 |
| Education & Childcare | 91 | 95 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $116,670 | $9,723 | $2,722 | $3,500 |
| Renters | $59,833 | $4,986 | $1,396 | $1,795 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| City | Population | Cost of Living Index | National Avg. |
| Tarrants, MO | 0 | 96 | 4.0% |
| Ashburn, MO | 0 | 99 | 1.4% |
| Annada, MO | 61 | 96 | 4.0% |
| Nebo, IL | 373 | 72 | 27.8% |
| Hamburg, IL | 159 | 79 | 21.2% |
| Clarksville, MO | 525 | 79 | 21.1% |
| City | Population | Cost of Living Index | National Avg. |
| La Paz Valley, AZ | 525 | 103 | 2.6% |
| Buckley, IL | 525 | 86 | 14.3% |
| Reynolds, IN | 525 | 85 | 15.4% |
| Grosse Tete, LA | 525 | 88 | 12.0% |
| South Range, MI | 525 | 83 | 17.3% |
| Clarksville, MO | 525 | 79 | 21.1% |