| Index | Chillicothe | Ohio | National |
| Average Test Scores | 57% | 61% | 48% |
| Student/Teacher ratio | 20:1 | 17:1 | 16:1 |
| Total public schools | 23 | 3,650 | 79,221 |
| Total private schools | 3 | 1,000 | 24,874 |
| Total post-secondary schools | 3 | 393 | 7,963 |

| Index | Chillicothe | Ohio | National |
| Completed 8th grade | 82.4% | 86.9% | 84.3% |
| Completed high school | 81.3% | 85.6% | 83.0% |
| Completed some college | 45.8% | 55.7% | 59.4% |
| Completed associate degree | 27.2% | 35.1% | 38.5% |
| Completed bachelors | 18.7% | 26.7% | 30.3% |
| Completed masters | 7.3% | 10.0% | 11.5% |
| Completed professional degree | 2.2% | 2.7% | 3.3% |
| Completed doctorate | 0.5% | 1.1% | 1.3% |
There are a total of 23 public schools, 3 private schools and 3 post-secondary schools in Chillicothe. Using the proficiency score averages, the average test scores for Chillicothe, OH schools is 57%. The average student to teacher ratio is 20:1. In Chillicothe, OH, an average of 82.4% of students have completed 8th grade and an average of 81.3% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Kingston, OH | 976 | 69% | 42.7% |
| Laurelville, OH | 538 | 62% | 29.2% |
| Frankfort, OH | 1,360 | 58% | 21.5% |
| Waverly, OH | 4,307 | 49% | 1.7% |
| Chillicothe, OH | 22,213 | 57% | 18.7% |
| City | Population | Avg. Test Scores | National Avg. |
| Prichard, AL | 22,203 | 31% | 36.3% |
| Hamtramck, MI | 22,199 | 25% | 47.8% |
| South Euclid, OH | 22,242 | 59% | 22.2% |
| Anniston, AL | 22,178 | 39% | 18.4% |
| Kapolei, HI | 22,175 | 49% | 2.4% |
| Chillicothe, OH | 22,213 | 57% | 18.7% |