| Index | Chillicothe | Ohio | National |
| Income per capita | $43,077 | $41,785 | $44,883 |
| Median household income | $67,503 | $75,222 | $81,333 |
| Median income owner occupied | $99,318 | $98,843 | $106,172 |
| Median income renter occupied | $43,689 | $43,469 | $52,080 |
| Median earnings male | $59,135 | $53,201 | $54,343 |
| Median earnings female | $37,024 | $36,192 | $38,439 |
| Unemployment rate | 3.6% | 4.8% | 4.9% |
| Poverty level | 18.1% | 15.4% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 7.6% | 7.6% |
| Manufacturing sector | 24.5% | 24.5% |
| Financial & insurance services | 2.5% | 2.5% |
| Wholesale & retail services | 16.0% | 16.0% |
| Public administration | 6.6% | 6.6% |
| Transportation, warehousing & utilities | 6.5% | 6.5% |
| Education, health & social services | 16.3% | 16.3% |
| Other | 19.2% | 19.2% |
| City | Population | Household Income | National Avg. |
| Andersonville, OH | 605 | $141,706 | 74.2% |
| Tarlton, OH | 306 | $101,046 | 24.2% |
| Frankfort, OH | 1,360 | $67,317 | 17.2% |
| Adelphi, OH | 385 | $67,002 | 17.6% |
| Waverly, OH | 4,307 | $66,956 | 17.7% |
| Chillicothe, OH | 22,213 | $67,503 | 17.0% |
| City | Population | Household Income | National Avg. |
| Prichard, AL | 22,203 | $44,986 | 44.7% |
| Hamtramck, MI | 22,199 | $44,242 | 45.6% |
| Ballenger Creek, MD | 22,229 | $143,159 | 76.0% |
| St. Andrews, SC | 22,188 | $55,741 | 31.5% |
| Mont-Royal, QC | 22,238 | n/a | |
| Chillicothe, OH | 22,213 | $67,503 | 17.0% |