| Index | Cape Girardeau | Missouri | National |
| Income per capita | $37,916 | $39,715 | $44,883 |
| Median household income | $69,279 | $72,613 | $81,333 |
| Median income owner occupied | $102,587 | $90,986 | $106,172 |
| Median income renter occupied | $40,764 | $45,210 | $52,080 |
| Median earnings male | $39,304 | $52,324 | $54,343 |
| Median earnings female | $30,918 | $36,971 | $38,439 |
| Unemployment rate | 2.9% | 4.4% | 4.9% |
| Poverty level | 22.9% | 15.3% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 8.1% | 8.1% |
| Manufacturing sector | 11.1% | 11.1% |
| Financial & insurance services | 2.3% | 2.3% |
| Wholesale & retail services | 16.5% | 16.5% |
| Public administration | 3.8% | 3.8% |
| Transportation, warehousing & utilities | 3.7% | 3.7% |
| Education, health & social services | 21.0% | 21.0% |
| Other | 31.1% | 31.1% |
| City | Population | Household Income | National Avg. |
| Dutchtown, MO | 113 | $133,642 | 64.3% |
| Gordonville, MO | 487 | $98,748 | 21.4% |
| Benton, MO | 904 | $96,947 | 19.2% |
| Jackson, MO | 15,346 | $94,975 | 16.8% |
| Kelso, MO | 592 | $80,437 | 1.1% |
| Cape Girardeau, MO | 41,479 | $69,279 | 14.8% |
| City | Population | Household Income | National Avg. |
| Spanish Fork, UT | 41,496 | $117,922 | 45.0% |
| Holyoke, MA | 41,439 | $63,038 | 22.5% |
| Charlottetown, PE | 41,537 | n/a | |
| The Acreage, FL | 41,413 | $127,439 | 56.7% |
| Streamwood, IL | 41,397 | $130,562 | 60.5% |
| Cape Girardeau, MO | 41,479 | $69,279 | 14.8% |