| Index | Wapello | Iowa | National |
| Cost of living | 85 | 89 | 100 |
| Groceries | 95 | 97 | 100 |
| Health care | 98 | 96 | 100 |
| Housing | 59 | 74 | 100 |
| Transportation | 98 | 97 | 100 |
| Utilities | 96 | 95 | 100 |
| Lifestyle & Entertainment | 95 | 95 | 100 |
| Household Items | 95 | 97 | 100 |
| Education & Childcare | 96 | 94 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $123,741 | $10,312 | $2,887 | $3,713 |
| Renters | $93,699 | $7,808 | $2,186 | $2,811 |
| State | General Sales Tax | With Max Surtax |
| Iowa | 6% | 7% |
| State | Income Tax (Low) | Income Tax (High) |
| Iowa | 4.4% | 6% |
| City | Population | Cost of Living Index | National Avg. |
| Keithsburg, IL | 538 | 80 | 20.2% |
| Mount Union, IA | 140 | 79 | 20.7% |
| Conesville, IA | 553 | 81 | 19.4% |
| New Boston, IL | 530 | 84 | 15.7% |
| Fredonia, IA | 243 | 82 | 18.4% |
| Wapello, IA | 1,960 | 85 | 14.9% |
| City | Population | Cost of Living Index | National Avg. |
| Laurium, MI | 1,960 | 83 | 16.9% |
| Como, MS | 1,960 | 85 | 14.8% |
| Palm Valley, TX | 1,960 | 103 | 2.6% |
| Murfreesboro, AR | 1,959 | 80 | 19.5% |
| Toro Canyon, CA | 1,959 | 343 | 243.0% |
| Wapello, IA | 1,960 | 85 | 14.9% |