| Index | Vandalia | Missouri | National |
| Average Test Scores | 38% | 44% | 48% |
| Student/Teacher ratio | 13:1 | 14:1 | 16:1 |
| Total public schools | 2 | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |

| Index | Vandalia | Missouri | National |
| Completed 8th grade | 65.0% | 86.0% | 84.3% |
| Completed high school | 61.4% | 84.2% | 83.0% |
| Completed some college | 29.7% | 57.7% | 59.4% |
| Completed associate degree | 10.5% | 35.2% | 38.5% |
| Completed bachelors | 6.3% | 27.6% | 30.3% |
| Completed masters | 1.5% | 10.4% | 11.5% |
| Completed professional degree | 0.5% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of 2 public schools, n/a private schools and n/a post-secondary schools in Vandalia. Using the proficiency score averages, the average test scores for Vandalia, MO schools is 38%. The average student to teacher ratio is 13:1. In Vandalia, MO, an average of 65.0% of students have completed 8th grade and an average of 61.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Frankford, MO | 464 | 70% | 45.8% |
| Center, MO | 485 | 46% | 5.2% |
| Laddonia, MO | 599 | 37% | 22.9% |
| Vandalia, MO | 3,993 | 38% | 20.3% |
| City | Population | Avg. Test Scores | National Avg. |
| Menands, NY | 3,993 | 55% | 13.5% |
| Washington Park, IL | 3,994 | 19% | 60.4% |
| Crandall, TX | 3,995 | 47% | 2.3% |
| Benson, NC | 3,991 | 33% | 30.4% |
| Huxley, IA | 4,000 | 83% | 71.9% |
| Vandalia, MO | 3,993 | 38% | 20.3% |