| Index | Sistersville | West Virginia | National |
| Average Test Scores | n/a | n/a | 48% |
| Student/Teacher ratio | 14:1 | 15:1 | 16:1 |
| Total public schools | 3 | 509 | 79,221 |
| Total private schools | n/a | 115 | 24,874 |
| Total post-secondary schools | n/a | 78 | 7,963 |

| Index | Sistersville | West Virginia | National |
| Completed 8th grade | 79.1% | 80.9% | 84.3% |
| Completed high school | 77.4% | 78.6% | 83.0% |
| Completed some college | 40.5% | 44.9% | 59.4% |
| Completed associate degree | 23.5% | 26.3% | 38.5% |
| Completed bachelors | 16.3% | 19.6% | 30.3% |
| Completed masters | 5.8% | 7.7% | 11.5% |
| Completed professional degree | 2.1% | 2.1% | 3.3% |
| Completed doctorate | 0.5% | 0.8% | 1.3% |
There are a total of 3 public schools, n/a private schools and n/a post-secondary schools in Sistersville. Using the proficiency score averages, the average test scores for Sistersville, WV schools is n/a. The average student to teacher ratio is 14:1. In Sistersville, WV, an average of 79.1% of students have completed 8th grade and an average of 77.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Newport, OH | 1,357 | 77% | 60.4% |
| Graysville, OH | 69 | 67% | 39.6% |
| Matamoras, OH | 1,084 | 57% | 18.8% |
| Hannibal, OH | 304 | 48% | 1.0% |
| Woodsfield, OH | 2,408 | 47% | 2.6% |
| Sistersville, WV | 1,375 | n/a |
| City | Population | Avg. Test Scores | National Avg. |
| Eustace, TX | 1,375 | 51% | 5.9% |
| Albion, PA | 1,375 | 67% | 38.5% |
| Walnut, IL | 1,376 | 24% | 50.0% |
| Cavalier, ND | 1,374 | 46% | 4.7% |
| Millbrook, NY | 1,376 | 68% | 41.7% |
| Sistersville, WV | 1,375 | n/a |