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| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 26°F | 48°F | 35°F | 1.7" |
| February | 29°F | 51°F | 39°F | 1.7" |
| March | 40°F | 63°F | 50°F | 3.5" |
| April | 48°F | 71°F | 59°F | 5.6" |
| May | 57°F | 78°F | 67°F | 7.3" |
| June | 67°F | 88°F | 77°F | 6.2" |
| July | 70°F | 92°F | 80°F | 4.0" |
| August | 69°F | 91°F | 79°F | 4.6" |
| September | 61°F | 83°F | 71°F | 4.7" |
| October | 49°F | 72°F | 59°F | 3.9" |
| November | 39°F | 61°F | 49°F | 2.9" |
| December | 29°F | 49°F | 38°F | 2.7" |
| Index | Seneca | Missouri | National |
| Air quality index | 38 | 97 | 42 |
| Pollution index | 703,846 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 363 |
| Days with good air quality | 289 |
| Days with moderate air quality | 73 |
| Days w/ poor A.Q. for sensitive groups | 1 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.000% |
| Benzene | 0.010% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.002% |
| Mercury | 0.250% |
| City | Population | Air Quality Index | National Avg. |
| Lowell, KS | 228 | 37 | 26.0% |
| Redings Mill, MO | 105 | 37 | 26.0% |
| Dennis Acres, MO | 57 | 37 | 26.0% |
| Saginaw, MO | 341 | 37 | 26.0% |
| Grand Falls Plaza, MO | 133 | 37 | 26.0% |
| Seneca, MO | 2,229 | 38 | 24.0% |
| City | Population | Air Quality Index | National Avg. |
| Lake Placid, NY | 2,229 | 37 | 26.0% |
| Cave City, AR | 2,228 | 36 | 28.0% |
| Cayucos, CA | 2,228 | 46 | 8.0% |
| Mangonia Park, FL | 2,228 | 36 | 28.0% |
| Sainte-Cécile-de-Milton, QC | 2,228 | n/a | |
| Seneca, MO | 2,229 | 38 | 24.0% |
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