| Index | Seneca | Missouri | National |
| Average Test Scores | 35% | 44% | 48% |
| Student/Teacher ratio | 15:1 | 14:1 | 16:1 |
| Total public schools | 3 | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |

| Index | Seneca | Missouri | National |
| Completed 8th grade | 85.1% | 86.0% | 84.3% |
| Completed high school | 83.4% | 84.2% | 83.0% |
| Completed some college | 49.5% | 57.7% | 59.4% |
| Completed associate degree | 27.2% | 35.2% | 38.5% |
| Completed bachelors | 18.4% | 27.6% | 30.3% |
| Completed masters | 5.0% | 10.4% | 11.5% |
| Completed professional degree | 0.0% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of 3 public schools, n/a private schools and n/a post-secondary schools in Seneca. Using the proficiency score averages, the average test scores for Seneca, MO schools is 35%. The average student to teacher ratio is 15:1. In Seneca, MO, an average of 85.1% of students have completed 8th grade and an average of 83.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Anderson, MO | 2,450 | 49% | 1.0% |
| Neosho, MO | 12,375 | 45% | 6.0% |
| Fairland, OK | 1,221 | 39% | 19.1% |
| Baxter Springs, KS | 4,057 | 35% | 28.1% |
| Goodman, MO | 1,493 | 35% | 28.1% |
| Seneca, MO | 2,286 | 35% | 27.6% |
| City | Population | Avg. Test Scores | National Avg. |
| Polo, IL | 2,286 | 39% | 19.1% |
| Kellogg, ID | 2,287 | 41% | 15.1% |
| Gibbsboro, NJ | 2,285 | 45% | 7.3% |
| Vale, OR | 2,287 | 53% | 10.7% |
| Myersville, MD | 2,284 | 57% | 18.8% |
| Seneca, MO | 2,286 | 35% | 27.6% |