Second Mesa, AZ has a population of 1,537 and is the 12,538th largest city in the United States. The population density is 38 per sq mi which is 33% lower than the Arizona average and 58% lower than the national average. The median age in Second Mesa is 28 which is approximately 25% lower than the Arizona average of 37. In Second Mesa, 44% of the population over 15 years of age are married, 20% speak English and 0% speak Spanish. 95% of Second Mesa residents were born in Arizona, 4% were born out of state, 0% were born outside of the United States and 1% were foreign born.