Potrero, CA has a population of 453 and is the 20,161st largest city in the United States. The population density is 144 per sq mi which is 38% lower than the California average and 59% higher than the national average. The median age in Potrero is 35 which is approximately 2% lower than the California average of 36. In Potrero, 68% of the population over 15 years of age are married, 34% speak English and 66% speak Spanish. 53% of Potrero residents were born in California, 22% were born out of state, 0% were born outside of the United States and 26% were foreign born.