Pickens, SC has a population of 3,166 and is the 8,537th largest city in the United States. The population density is 1,120 per sq mi which is 659% higher than the South Carolina average and 1136% higher than the national average. The median age in Pickens is 40 which is approximately 3% higher than the South Carolina average of 39. In Pickens, 46% of the population over 15 years of age are married, 100% speak English and 0% speak Spanish. 71% of Pickens residents were born in South Carolina, 29% were born out of state, 0% were born outside of the United States and 0% were foreign born.