| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 24°F | 54°F | 37°F | 2.8" |
| February | 27°F | 59°F | 41°F | 1.5" |
| March | 35°F | 69°F | 50°F | 4.5" |
| April | 41°F | 75°F | 57°F | 2.1" |
| May | 50°F | 82°F | 65°F | 6.1" |
| June | 61°F | 91°F | 75°F | 6.9" |
| July | 64°F | 91°F | 77°F | 4.5" |
| August | 63°F | 90°F | 75°F | 6.2" |
| September | 56°F | 83°F | 68°F | 3.8" |
| October | 45°F | 75°F | 58°F | 4.6" |
| November | 33°F | 64°F | 47°F | 0.8" |
| December | 26°F | 53°F | 37°F | 2.3" |
| Index | Muleshoe | Texas | National |
| Air quality index | 25 | 52 | 42 |
| Pollution index | 254,818 | 2,009,300 | 2,726,193 |
| Measurement | Total |
| Days measured | 330 |
| Days with good air quality | 316 |
| Days with moderate air quality | 13 |
| Days w/ poor A.Q. for sensitive groups | 1 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.000% |
| Benzene | 0.004% |
| Carbon Tetrachloride | 0.000% |
| Lead | 0.001% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Sudan, TX | 1,102 | 25 | 50.0% |
| Muleshoe, TX | 5,668 | 25 | 50.0% |
| City | Population | Air Quality Index | National Avg. |
| Connell, WA | 5,667 | 37 | 26.0% |
| Waynesboro, GA | 5,670 | 47 | 6.0% |
| Somerdale, NJ | 5,665 | 51 | 2.0% |
| Atlanta, TX | 5,665 | 39 | 22.0% |
| Meadow Lake, SK | 5,663 | n/a | |
| Muleshoe, TX | 5,668 | 25 | 50.0% |
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