| Index | Middletown | Missouri | National |
| Average Test Scores | n/a | 44% | 48% |
| Student/Teacher ratio | n/a | 14:1 | 16:1 |
| Total public schools | n/a | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | Middletown | Missouri | National |
| Completed 8th grade | 60.1% | 86.0% | 84.3% |
| Completed high school | 57.4% | 84.2% | 83.0% |
| Completed some college | 26.4% | 57.7% | 59.4% |
| Completed associate degree | 6.8% | 35.2% | 38.5% |
| Completed bachelors | 3.4% | 27.6% | 30.3% |
| Completed masters | 0.7% | 10.4% | 11.5% |
| Completed professional degree | 0.0% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Middletown. Using the proficiency score averages, the average test scores for Middletown, MO schools is n/a. The average student to teacher ratio is n/a. In Middletown, MO, an average of 60.1% of students have completed 8th grade and an average of 57.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Montgomery City, MO | 2,765 | 46% | 5.2% |
| Bowling Green, MO | 5,376 | 44% | 9.4% |
| Vandalia, MO | 3,993 | 38% | 20.3% |
| Laddonia, MO | 599 | 37% | 22.9% |
| Wellsville, MO | 1,176 | 35% | 28.1% |
| Middletown, MO | 222 | n/a |
| City | Population | Avg. Test Scores | National Avg. |
| Hendrum, MN | 222 | 75% | 56.3% |
| Rye, CO | 222 | 52% | 8.9% |
| Pecan Gap, TX | 222 | 30% | 37.5% |
| Franktown, CO | 221 | 60% | 24.5% |
| Port Murray, NJ | 223 | 47% | 2.1% |
| Middletown, MO | 222 | n/a |
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